BDBM50374253 CHEMBL403195

SMILES COC[C@H]1CCCN1C(=O)c1cc(C)cc(c1)C(=O)N[C@@H](Cc1cc(F)cc(F)c1)[C@H](O)[C@H]1C[C@H](CN1)Oc1ccccc1

InChI Key InChIKey=KYHYNSQLYDXSNK-MXWGZHRFSA-N

Data  3 IC50

PDB links: 1 PDB ID matches this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50374253   

TargetBeta-secretase 1(Homo sapiens (Human))
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50374253(CHEMBL403195)
Affinity DataIC50:  0.700nMAssay Description:Inhibition of BACE1More data for this Ligand-Target Pair
TargetBeta-secretase 1(Homo sapiens (Human))
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50374253(CHEMBL403195)
Affinity DataIC50:  21nMAssay Description:Inhibition of BACE1 in human HEK293 cells assessed as inhibition of amyloid beta 40 productionMore data for this Ligand-Target Pair